Raul Isea

Citations   Isea, R. (2024). Can Non-Heart Diseases like Diabetes and Sleep Apnea be Detected by an ECG. Virol Res Rev, 1(1), 01-06 PDF:  https://www.opastpublishers.com/open-access-articles/can-nonheart-diseases-like-diabetes-and-sleep-apnea-be-detected-by-an-ecg.pdf Abstract An electrocardiogram (ECG) is frequently used to identify heart problems, but it can also identify apnea, diabetes, and other conditions that are not heart-related. The study uses deep learning methods from artificial intelligence, particularly the Convolutional Neural Network (CNN) approach, to look for patterns in ECG data. To predict illness, two different methodologies are used. The first approach makes use of an ECG scale, while the second employs a gradient-boosting machine (GBM)-based learning technique. The MIT-BIH Arrhythmia database, the Normal Sinus Rhythm database, the BIDMC Congestive Heart Failure database, the Sleep Apnea database, the type 2 diabetes mellitus dataset, and the dataset for healthy v

  Citation : Raúl Isea (2021) Analytical Solutions of the Transmissibility of the SARS-CoV-2 in Three Interactive Populations. International Journal of Coronaviruses - 2(4):1-8. https://doi.org/10.14302/issn.2692-1537.ijcv-21-3732 PDF:  https://openaccesspub.org/article/1571/ijcv-21-3732.pdf Abstract This paper resolves analytically a mathematical model that reproduces the transmission of Covid-19 in three interactive populations, i.e. from the initial source of contagion associated with the bat population, subsequently transmitted to unknown host (usually associate with pangolins). The host were sent and distributed to Seafood Market in Wuhan (defined reservoir), and finally infected to the human population. The model is based on a system of ten differential equations reproducing all the possible infection scenarios among all of them, that is: (1) there is no infection in any of the three populations, (2) only the population of bats is infected, (3) only the pangolins, (4) only the hu

  Citation : Isea, R. (2021). ¿Hubo fraude electoral en las elecciones presidenciales de los Estados Unidos en 2020? Was there voter fraud in the 2020 United States presidential elections?. Conocimiento Libre Y Licenciamiento (CLIC), (24).  PDF:  https://convite.cenditel.gob.ve/revistaclic/index.php/revistaclic/article/view/1087 Resumen El trabajo realiza un estudio forense de los votos registrados en la elección presidencial de los Estados Unidos realizada el 3 de noviembre de 2020, para determinar si hubo fraude tras las continuas declaraciones del ex-presidente Donald Trump. Para ello, se analizaron el total de los votos obtenidos por estado en dos momentos diferentes, es decir, el acumulado de votos hasta el 18 de noviembre, y el total obtenido en la contienda. En ambos casos, no se detectaron sospechas de manipulación de los datos. En paralelo, se analizaron los votos acumulados hasta el 18 de noviembre en varios condados a medida que se iban totalizando por estado, y se detectó q

  Citation : Raúl Isea (2021) A Missing Data on Covid-19 Forecasts. International Journal of Coronaviruses - 3(2):27-31. https://doi.org/10.14302/issn.2692-1537.ijcv-21-3918 PDF:  https://openaccesspub.org/article/1685/ijcv-21-3918.pdf Abstract Mathematical and computational studies of Covid-19 have underestimated the influence that other countries have on their daily records. To visualize this, a Granger causality analysis was implemented in Python to determine if the cases registered in Brazil, Chile, Colombia, Ecuador, Panama, Paraguay, Peru and the USA have any effect on Venezuela, and between all of them. Finally, this paper highlights the need to incorporate causality analysis employing only the cases of Covid-19 to improve mid and long term forecasts.

  Citation : Raúl Isea, Jesús Isea (2021) Was there voter fraud in the 2021 Peru Presidential Elections?. Journal of Model Based Research - 1(4):1-5. https://doi.org/10.14302/issn.2643-2811.jmbr-21-3954 PDF:  https://openaccesspub.org/article/1713/jmbr-21-3954.pdf Abstract This paper performs a forensic study of the Peru’s presidential election on June 6th, 2021 between Pedro Castillo and Keiko Fujimori, where ex-candidate Keiko Fujimori claimed there had been irregularities. We calculate three p-values that help us determine if there was fraud. The consensus of the results indicates that there was no manipulation of the results.

  Citation : Raúl Isea (2022) What Could Represent the Mantissa of the Registered Covid-19 Cases?. International Journal of Coronaviruses - 4(2):1-6. https://doi.org/10.14302/issn.2692-1537.ijcv-22-4108 PDF:  https://openaccesspub.org/article/1783/ijcv-22-4108.pdf Abstract In this work we present how it is possible to visualize the different coronavirus outbreaks from the calculation of the mantissa from the daily record of cases by Covid-19.This curve can also indicate the speed of propagation of the disease from the calculated infection rate. These conclusions are derived from the respective calculations in four different countries: Australia, Brazil, Italy, and Venezuela.

  Citation : Raúl Isea, Rafael Mayo-García (2022) First Analytical Solution of Intracellular life Cycle of SARS-CoV-2. Journal of Model Based Research - 1(4):6-12. https://doi.org/10.14302/issn.2643-2811.jmbr-22-4130 PDF:   https://openaccesspub.org/article/1801/jmbr-22-4130.pdf Abstract The goal of this paper is to show that it is possible to obtainan analytical solution of the life cycle of SARS-CoV-2 based on a deterministic model. To do this, this work solved a system of twelve differential equations where we obtained two points of equilibrium. The first critical point corresponds to the initial conditions regarding the virus entry into the cell without replication in the cell, and the second involved one is the process of the transcription and replication of the virus in the infected cell.

  Citation : Raúl Isea, Rafael Mayo-García (2022) Analysis of Covid-19 Using A Modified SEIR Model To Understand The Cases Registered in Singapore, Spain, And Venezuela. Journal of Model Based Research - 1(4):13-22. https://doi.org/10.14302/issn.2643-2811.jmbr-22-4258 PDF:  https://openaccesspub.org/article/1864/jmbr-22-4258.pdf Abstract This work proposes a modification of a compartmental-type model based on the Susceptible-Exposed-Infected-Recovered (SEIR) scheme to describe the dynamics of contagion by Covid-19 in any part of the world, including also the numerical and analytical calculation of the mantissa and the resolution of a partial differential equation system. As an example, the different incidents that occurred in Singapore, Spain and Venezuela are analyzed to demonstrate the usefulness of the methodology developed in this work that can be seamlessly extended to other regions.

  Citation : Raúl Isea (2023) Classification and Prioritization of Tasks in Public Administration. Journal of Current Scientific Research - 2(1):18-23. https://doi.org/10.14302/issn.2766-8681.jcsr-23-4526 PDF:  https://openaccesspub.org/article/1970/jcsr-23-4526.pdf Abstract A large volume of data is being generated in public administration and it is necessary to develop new computational methodologies to classify and analyze it to do a better analysis and decision making. For this reason, the goal of this paper is to present a computational methodology that allows classifying and prioritizing a series of complaints using Artificial Intelligence techniques. To test this model, we generate 600 complaints in four sectors of the public administration to prove the concept. Later, we calculated the tree decision with the help of the Confusion Matrix, and finally the Priority Matrix (based on the Eisenhower model) allows setting priorities on the complaints, and offers the possibility of del

  Citation : Raúl Isea, Rafael Mayo-García (2023) A Data Mining Methodology for Detecting Conspiracy Theories from Scientific Articles: The Covid-19 Case. International Journal of Coronaviruses - 4(4):22-31. https://doi.org/10.14302/issn.2692-1537.ijcv-23-4586 PDF:  https://openaccesspub.org/article/1971/ijcv-23-4586.pdf Abstract The goal is to do a text mining analysis of all scientific publications and find out what journal and what aspects are studying about the conspiracy theories of Covid-19. For this purpose, all publications available in the National Center for Biotechnology Information (NCBI) database were consulted as they were peer-reviewed papers. Of all these papers, only the abstracts of each one were studied using artificial intelligence techniques to determine, for example, whether the subject is of importance depending on the journals where it has been published, and above all, what possible relationships could be extracted from the information published in them. In add

  Citation : Raul Isea(2023). A General Approach to Modeling Covid-19. Journal of Model Based Research – 2(2):1-19. https://doi.org/10.14302/issn.2643-2811.jmbr-23-4556 PDF:  https://openaccesspub.org/article/1977/jmbr-23-4556.pdf Abstract The present work shows that it is possible to analytically solve a general model to explain the transmission dynamics of SARS-CoV-2. First, the within-host model is described, and later a between-host model, where the coupling between them is the viral load of SARS-CoV-2. The within-host model describes the equations involved in the life cycle of SARS-CoV-2, and also the immune response; while that the between-Host model analyzes the dynamics of virus spread from the original source of contagion associated with bats, subsequently transmitted to a host, and then reaching the reservoir (Huanan Seafood Wholesale Market in Wuhan ), until finally infecting the human population

  Citation : Raúl Isea(2023).Stylometric analysis of Lafond's letter that never wrote Simón Bolívar to San Martín, Journal of Current Scientific Research -2(1):24-30. https://doi.org/10.14302/issn.2766-8681.jcsr-23-4727 PDF:  https://cvraulisea.files.wordpress.com/2023/10/jcsr-23-4727.pdf Abstract The goal is to analyze that Lafond’s letter by stylometric methods, supposedly written by Simón Bolívar to General San Martín about the destiny of Ecuador. The Delta function was calculated after evaluating 16 letters from Simón Bolívar and including another 11 letters from San Martín. The reason for including San Martín’s letter was to verify if the method used could distinguish between the two authors. A linguistic corpus was constructed using functional words, and a dendrogram was used to visualize the result. Finally, it is concluded that the letter to Lafond is false. Simón Bolívar never wrote this letter

  Citation : Raul Isea (2023). Can Data-Driven  Hypotheses Replace The Scientific Method?. Journal of Big Data Research – 1(3):12-19. https:// doi.org/10.14302/issn.2768-0207.jbr-23-4753 PDF:  https://cvraulisea.files.wordpress.com/2023/10/jbr-23-4753_2.pdf Abstract The rapid growth of data and scientific journals has led to the promotion of data-based hypotheses. Data-driven hypotheses can also be used to establish new scientific laws or confirm existing ones, demonstrating the foundation of this philosophy. To introduce this idea, this article presents a Python-based computational algorithm that can generate system dynamics equations without using working hypotheses.

  Citation : Raúl Isea (2023). A stylometric analysis of two sentimental letters by Albert Einstein and Simón Bolívar. Journal of Language Research-1(1):15-20 PDF:   https://cvraulisea.files.wordpress.com/2023/11/jlr-23-4739.pdf Abstract On social networks often circulate emotional letters from various authors that appear after their death. The supposed letter Albert Einstein wrote to his daughter Lieserl and the letter Simon Bolivar wrote to his cousin Fanny are two examples. A Python-developed tool is used to do a stylometric study to determine whether these authors were. The language styles of Einstein and Bolivar were described using eight and six letters, respectively. The results show that they never wrote these letters

Citation :  Isea R. (2023). We Continue to Battle with Diseases that are Difficult to Diagnose and Cure in the 21st Century. Mathews J Pharma Sci. 7(3):22.  PDF:  https://cvraulisea.files.wordpress.com/2023/10/we-continue-to-battle-with-diseases-that-are-difficult-to-diagnose-and-cure-in-the-21st-century.pdf Abstract: The Covid-19 pandemic has significantly impacted global health, with over 695 million people affected by September 2023. Despite extensive scientific research, the disease remains endemic, necessitating computer systems for research organization. Pregnant women, like a woman who died from influenza A, require vaccination, but the use of oseltamivir remains unclear. The Nipah virus, with a high mortality rate and no known cure, has caused closures and restrictions in India. Polo, a highly contagious disease, remains endemic in Pakistan, Afghanistan, and Egypt, with efforts focused on controlling and eliminating remaining types. The situation is complicated by lack of vacci

  Citation : Raúl Isea (2023) Biotechnology 2.0. Journal of Current Scientific Research - 2(2):1-7. https://doi.org/10.14302/issn.2766-8681.jcsr-23-4811 PDF:  https://openaccesspub.org/article/2037/jcsr-23-4811.pdf Abstract Biotechnology has changed our relationships and perspectives of the world, influencing industry and serving as a catalyst for scientific discoveries. With this change, biotechnology enters a new age known as Biotechnology 2.0. "Modern Biotechnology" and "Artificial Intelligence" are getting married. In order to lessen food poverty, this idea incorporates the most recent advancements in genetic engineering, medicine, environmental preservation, and agricultural productivity and loss reduction strategies. The importance of openness and public involvement in addressing public concerns and advancing moral behavior in biotechnology's future, fostering cooperation among diverse stakeholders, and accomplishing this in a sustainable way for the good

Citation: Isea R. Is it possible to develop a vaccine against depression based on microRNA? Pharm Pharmacol Int J. 2023;11(5):179‒181.  PDF:   Is it possible to develop a vaccine against depression based on microRNA? Abstract It is difficult to create vaccinations to prevent mental diseases like depression because of their complex underlying mechanisms. In order to create an effective vaccine, the underlying causes of these diseases must be understood. In addition, it has been observed that microRNAs are crucial regulators of various cell functions, including proliferation, growth, differentiation, neoplastic transformation, and tissue regeneration. Their importance goes beyond posttranscriptional control of gene expression. In light of this, the study recommends employing microRNA in the production of live-attenuated vaccines to produce strong, long-lasting immunity against mental diseases.

  Citation : Raul Isea (2023) Is Vagus Nerve Therapy a Potential Alzheimer's Disease Treatment?. International Journal of Global Health - 2(1):40-42. https://doi.org/10.14302/issn.2693-1176.ijgh-23-4854 PDF:  https://openaccesspub.org/ijgh/article/2054 Abstract A potential treatment for Alzheimer's disease is vagus nerve therapy, which has been made possible by considerable advances in neuroscience. An essential component of the autonomic nervous system, the vagus nerve regulates memory, inflammation, and cognition. Researchers hope to delay the progression of Alzheimer's disease and improve cognitive function by implanting a vagus nerve stimulator (VNS). Alzheimer's patients have higher heart rate variability, according to an ECG study, which may be advantageous. To completely grasp its mechanics and long-term effectiveness, more research is necessary.

  R. Isea* (2024) « Newborns’ microRNA expression as potential biomarkers for disease diagnosis «.  International Journal of Neonatology. Vol 1(1), 22 . R. Isea* (2024). « A systematic review of dengue fever and dengue-associated neurological conditions was conducted in an attempt to better understand this disease «. Journal of Bioinformatics and Diabetes. Vol. 2(1), 1. R. Isea* (2024). « Toward A Diet Based on MicroRNA «.  International Journal of Nutrition. Vol. 8(1), 36. R. Isea* (2024). " What can a stylometric analysis contribute to the Diary of Saint Faustina Kowalska?" Acepted. R. Isea* (2024). " A Brief Summary of the Ways in Which our Genes Influence our Perceptions of Attraction and Love ". Archives Clin Med Microbiol, 3(2), 01-03. R. Isea* (2024).  « Artificial Intelligence Can Diagnose any Disease from the Data of  an   Electrocardiogram «.  J Biomed Sci Biotech Res. Vol. 2(1): 1 R. Isea* (2024).  « Can Non-Heart Diseases like Diabetes and Sleep Apnea b