A Proposal for a Cardiac Intelligent Patch that Uses MicroRNAs to Guide the Regeneration of Cardiac Tissues

Abstract

Developments in biotechnology, nanotechnology, and artificial intelligence (AI) have been playing a significant role in the design of an intelligent cardiac patch. This innovative device aims to offer a solution for future healthcare by offering a dynamic and personalized intervention model for heart disorders. The initial stage in its operation is surgical implantation into a biocompatible hydrogel scaffold that has been pre-seeded with iPSC-cardiomyocytes produced from the patient. In addition, the nanosensors were positioned strategically over the surrounding cardiac tissue continuously monitor its biochemical and physiological properties.  This data is received by an ultra-low-power processing module, which then evaluates it using pre-programmed algorithms.  Finally, there is genuine potential for functional regeneration and a significant improvement in patients' quality of life, further research is required to optimize miRNA processing with complex cassettes, increase the power efficiency of electrical modules, and improve the accuracy and stability of nanosensors in dynamic biological contexts.

Available at https://ejsmt.com/index.php/journal/article/view/18

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